Just kidding. This was a fine puzzle. Except for the EARWAX (63A: Swab target). I mean really, last week it was EGGSACS, this week it's earwax. And it's right on top of a (66A: Surgeon's aid) SPONGE. Stop grossing me out!
The theme today, such as it was, seemed a little, well... meh. The "reveal" clue, 25D: Vicissitudes of life, as for the inventor named in the circled squares?, seemed oddly phrased, but it referred, I guess, to the four circled instances of the name OTIS, contained within other words or combinations of words. It read down, then up twice, then down again. I first thought the two ups in the middle were odd, but they were at least progressive. By that I mean that the second up could have been seen as a continuation of an elevator ride, and the following down started above them both. But that's probably already too much contemplation of this topic.
If I ever make a puzzle, be on the lookout for the clue "Island so nice, they named it twice," which is what I wished had been the clue for BORABORA (65A: Island near Tahiti).
Sometimes you get SERA, sometimes SERUMS, for 24A: Hospital fluids. (Another gross one, come to think of it).
Lastly, I started this out by guessing cARbAR for 1A: Where some commuters drink (imagining, I guess, a limo), and then didn't get BAMA or CURATOR for quite some time. (Cama and burator just didn't seem to make any sense.) It got me to thinking - do commuters really drink in bar cars? I've gotta start taking the train more often!