A lovely Saturday grid full of interesting answers. We were saved from a DNF thanks to Frannie putting in the last A of AYLA (24A: Cro-Magnon orphan of literature) and ALEXA (9D: Internet traffic statistics company). We were once acquainted with one of the founders of ALEXA and the Internet Archive, by the way. And yes, I just name-dropped without actually name-dropping.
But back to the grid! PANOPLY (38D: Impressive range), ANATOLIA (36D: It was home to two Wonders of the Ancient World) (The Temple of Artemis at Ephesus and the Mausoleum of Halicarnassus), PATTYCAKE (44A: It involves hand-to-hand coordination), MAKEBANK (36D: Earn a load of money, in modern lingo)... all great. The clue for (the full name) TOMKITE (32A: U.S. Open champion whose last name is a toy) was great. And I liked how LEGALIZEIT (18A: Debut Peter Tosh album, and a rallying cry for pot smokers) crossed REEFER (12D: Joint).
So much good. DOOFUS/REEFER/AEROBE all side-by-side... there's almost no slop at all! There's that one square... we got it, but even if we hadn't, I think I'd still love this one.