Whew! Mr. Quigley can make a very difficult puzzle when he wants to, and we had to put this one down unfinished last night. This morning, we worked on the NE corner together and finally brought it home. The second T of LANOTTE (25D: 1961 Michelangelo Antonioni drama) (didn't he do "Blow Up"? … yes, yes he did, but I've never heard of this one) where it crosses STINE (45A: "A Midsummer Night's Scream" author) was an educated guess, but really, how many other letters could it have been, I guess. BESSEMER (7A: Sir Henry ____, pioneer in steelmaking), STAN (10D: Pollster Greenberg), and CARYN (30A: Figure skater Kadavy) were all unknowns, and we had EXITrAmp for a long time instead of EXITLANE (16A: Getting-off point), which didn't help things. REASON (14D: "The natural organ of truth": C. S. Lewis) (too bad his deserted him …) and ENERGY (13D: Cabinet department) were inferable, but not known. In short, the whole quadrant was very difficult for us. Perhaps you fared better.
Oh, and one last thing about that corner - TEXASTEA (18A: Drink made with tequila, rum, vodka, gin, bourbon, triple sec, sweet-and-sour mix and Coke) sounds dreadful. Does anyone, aside from, obviously, idiotic college kids, drink that?
Oh, wait, I forgot EXEDRA (8D: Semicircular recess in Roman architecture. I'm a Latin student and an architectural photographer, and this word is not in my general vocabulary. Plus, it crosses ONERS (25A: Standouts), which is itself a standout of a certain kind.
Whew! And on the bottom we have such gems as CRUMHORN (58A: Renaissance woodwind), GAFFS (47A: Barbed spears for fishing), and EDDA (49A: Classic work in Old Norse) (Frannie knew this one!, which helped a lot).
Another appropriate anagram of "notes" is "tones," but STENO (6D: Anagram of "notes," appropriately) is also good, and the S is better placed.
A tough puzzle with some rough spots, but overall, we finished, and that's always satisfying.