Who doesn't love ATLAS (102D: Mythological figure hinted at by the answers to the eight starred clues as well as this puzzle's design)? Nobody. And I guess by "this puzzle's design," they mean to imply that the central circle is meant to represent Earth. I guess that's fine, but the same puzzle could probably have been used with a Sisyphus theme. But I'm not complaining, I love all the theme material. There's the straightforward stuff - PILLAROFSTRENGTH (16D: *Comfort provider during difficult times) and WEIGHTOFTHEWORLD (37D: *Crushing burden), and then there's some humorous stuff SUPPORTINGACTOR (23A: *One who's not leading) and UPPERBACKPAIN (100A: *What a massage may relieve). Very nice.
The fill is good, too, with gems like SCATHES (27A: Excoriates), BEERSTEIN (43D: Something handled in a bar), REDLETTER (38D: Having special significance), DEEPWEB (78A: Content that's hard for a search engine to access), and my candidate for "clue of the week" - 7D: It's been shortening since 1911 (CRISCO). That alone would have made this puzzle all right by me.