So many wonderful colloquial phrases, including AMITOOLATE, NOTONEWORD (always reminds me of "Bullets Over Broadway"), and ICOMEINPEACE.
Also, the slang is excellent: MERCYRULE is a longstanding phrase, but I'd never seen HOTDESKED before. And PLAYERHATERS is pretty well established, but I more commonly see it only with the second half.
I was pretty sure that 1A would be OMANI, but was briefly held up by 1D: Shaped like this answer's first letter, say (OVAL), because I misread it as referring to the clue's first answer. Fortunately that old piece of crosswordese, ARIL, helped open the corner up.
25A: Tragic flaw for Oedipus (HUBRIS) is a wonderful ROI (reference of interest - c.f. Frannie's entry in our vocab post). That caused me to look up the definition, as I had an idea of what it meant but was uncertain. Hubris is excessive pride toward, or defiance of, the gods, leading to nemesis (downfall). In Oedipus's case, his hubris was that he could ignore the fate set in store for him by the gods, when all of his actions led directly to that fate. Tough situation, you might say.
39A: Teacher's sleeve, in a pinch (ERASER) made me chuckle. 30D: Pursues a passion? (MAKESLOVE) made me raise an eyebrow. But here, the meaning is the more Victorian concept of wooing, rather than engaging in physical amorous activity.
10D: Knowledge, or a means to acquire it (SCHOLARSHIP) is an example of a kind of clue that I am increasingly appreciative of. It highlights the flexibility of the English language (I'm assuming other languages also have some flexibility as well, but I think that English is more so).
I did not have to use BRUTEFORCE to finally finish the NW, but there was a moment where I was worried I was headed in that direction. Seeing SLAP helped open the rest. For a hot second I had CHoCKS and was trying to convince myself that it would work. Until I realized it was CHICKS.