Hello Mr. Markey!* A very nice theme, and tribute, to the "Road Movies" of HOPEANDCROSBY (24A: The film's headliners). Eighty theme squares is a lot, and they are everywhere, making this one almost all about the theme. So much theme puts the grid in a bit of a stranglehold, and leaves us with crosswordese like ANIS, ANIL, OPES, and EDDA. We also get the unfortunate ALINED (42D: In a row: var.), and the unfamiliar (to me, anyway) YODER (29D: Wisconsin v. ____ (Landmark 1972 case on religious freedom)). My last square was the O in that name, where it crosses AON (32A: Get an ____ (ace)), which took me a long while to understand.
Still, even with all the theme constrictions, there are several non-theme downs that I enjoyed. TUNDRA (5D: Much Arctic land) (for now!), BAYOU (28D: Louisiana inlet), and ACTUAL (23D: Real). MITTEN (35D: Hand warmer) and COPCAR (38D: Black-and-white) did not come to me quickly, and call me crazy, but I almost liked MMCCC (39D: The year 2300) for its craziness. If it had had a slightly more amusing clue I would have actually liked it. :)
Don't tell Frannie, but I can't say I've ever seen more than a clip or two of any Hope & Crosby movie. Still, though, they are classics, and I am impressed by this "double-theme." Sometimes, if the theme is enough - especially in an early-week grid - you can give the fill a lot of leeway. I think that's the case here.
p.s. Our friend Huygens will certainly love this puzzle, as he and his wife will be on the road to Bali in less than a year! Qatar yesterday, Bali today... what's left for tomorrow? Perhaps you should be on the lookout for your next exotic destination!