For me, the theme's sparkle fades in and out, although, dear readers, do let me know if I've missed something; that happens to me occasionally. As spelled out in the revealer, each theme answer is a common thing ANDES, literally, or in other words, with ES added to the end of it. It is also a mountain chain, but that's not important now. For example, "For the win" becomes FORTHEWINES (Why many people visit Napa?) That one didn't do much for me, but I did enjoy HOOVERDAMES. Ha! GUESSNOTES and BABYSITES less so. BEARCUBES seemed like a bit of a stretch.
On the other hand, I enjoyed most of the rest of the puzzle. I liked the four big down answers: BERNOULLI, ANGIOGRAM, WOMENSLIB, and my favorite, ALONETIME (Period enjoyed by an introvert - apt!). There were a few French answers for the francophiles among us (ce qui AIME les EAUX). And fun fill like STOAT, TRUCE, BOOTH, RASH, MUTED, and NIX.
I was not duped today by "Half of due" and I dropped UNO right in at 62D. I felt that my indupability, combined with the fact that I knew almost all the relevant factual answers, might have resulted in a faster solve time for me today - I was YDS AWAY from my best Tuesday time. But, as they say, HAI NSA is 20/20.
When AWLS said and done, there was maybe a TAB too many acronyms around the edges, but I'm sure it helped put the puzzle TOBED.