This was a fun one. I immediately thought of PERUSE for "Look over," SUV for "Many a 4WD ride," and, of course, NED for "Name on both 'The Simpsons' and 'South Park,'" but they just wouldn't fit, and I had the distinct impression that I was missing something.
Eventually, more "too short" guesses and the revealer, RUNSONEMPTY, allowed me to finally bridge the gap.
Speaking of lacunae, GURUNANAK (Founder of the Sikh religion) is a name I have never before seen or heard. I didn't even realize that it, too, should have its own gap - that the founder was Guru Nanak, who lived in Pakistan between the fifteenth and sixteenth centuries. From the Wikipedia, the fundamental beliefs of Sikhism" include the "unity of all humankind, engaging in selfless service, striving for social justice for the benefit and prosperity of all, and honest conduct and livelihood while living a householder's life." Sounds like he would have fit into today's society just fine. Of course, there's also something about "faith and meditation on the name of the one creator," which is where I imagine the conflicts might start. It seems to me that if religions could just let go of the insistence on reverence toward an imaginary being, and focus on just doing all the good things that are supposedly the will of that phantom, we might all be in a better place.
Anywhoo... when I finished this one, I didn't immediately get any notification. I instinctively looked around for a possible incorrect entry, even while wondering why it wouldn't have told me something was wrong if I were really done. Then I looked again at 21-, 36-, and 50-Across, and wondered if I needed to put in a particular word, like "nil," or all zeros, and what I eventually tried was dashes. I filled in about four of them (across two answers) and suddenly I got the "Congratulations" screen. Odd. Did anyone else have any similar trouble at the end?
One last thing - WOULDIEVER DRUNKDIAL Laura DERN or John CUSAK? You bet I would. They're two of my favorite actors!
And a shout out to "Not-so-great depression" (DENT). That's a great non-QMC.
Loved it. Great start to The Turn. Hope you enjoyed it too.